Having children after IVF at 40

The realities of modern life are such that, compared to the past century, the childbearing period has shifted significantly. Sometimes, only after 40 years, having achieved success in their careers and furnished their own home, many couples feel morally ready to become parents. Assisted reproductive technologies (ART), which are being improved day by day, come to their aid. THIS is a special IVF technique that allows you to get pregnant at the age of 50 with your own egg.

• “Stars” who gave birth after IVF
• What are the chances of IVF after 40 years?
• Factors that reduce the chance of successful IVF
• Chances of IVF with your own egg and donor egg
• How to increase the chances of fertilization with IVF
• PGD ​​of the embryo before transfer
• How long does it take to try IVF to get pregnant?

The content of the article

“Stars” who gave birth after IVF

In vitro fertilization after 40 years often ends in a positive result - the birth of a healthy child, and sometimes two at once. An example of this is many popular people who became parents only after reaching this age. So, Celine Dion, in order to become a mother for the second time, went for IVF, and after the sixth repetition of the protocol she was able to get pregnant, giving birth to twins at the age of 42 - Nelson and Eddie. Marcia Cross, star of Desperate Housewives, gave birth to twins at almost 45 years old. Singer Mariah Carey also passed away not far away, having given birth to a son and daughter at the age of 41. All the “stars” confidently say: all these efforts, efforts and experiences were worth it to get such a miracle!

What are the chances of IVF after 40 years?

In fact, reproductive specialists around the world indicate that IVF after 40 years is a very common practice.

Of course, the chance of success is less than before the age of 30, however, it is there:

• The supply of follicles—the structures from which eggs are formed—is formed during the prenatal period, that is, even before a woman is born. Not all follicles mature into full-fledged cells capable of being fertilized; nevertheless, more than a dozen of them “survive” to the age of 40-50 years for the average woman;
• Reproductive organs. Neither the structure of the fallopian tubes nor the muscular lining of the uterus will change dramatically with age. Only the thickness of the endometrium (inner uterine lining) may change, but this is corrected during the IVF protocol.

Thus, if you carry out IVF at 40 years old, 9% is an approximate guarantee of giving birth to a healthy child. Don't rush to get upset over a small number. The fact is that even at 25 years old, the extracorporeal technique gives only a 48% chance of successful fertilization and implantation of embryos.

Factors that reduce the chance of successful IVF

Modern technologies have advanced so much that medicine knows cases of IVF at 50 years old with one’s own egg, which ended in successful birth. However, there are several main factors that significantly reduce the chance of success for older couples. Let's take a closer look.

Presence of inflammatory diseases of the pelvic organs

Hypothermia, any intrauterine interventions, unprotected sexual intercourse with different partners or one infected person are all causes of the development of inflammatory diseases of the uterus and its appendages. The body fights the existence of infection by changing pH, local temperature, and calling in immune cells.

• existing at the time of IVF, local factors will contribute to the removal of embryos from the uterine cavity;
• Often developing before the IVF planning stage, inflammatory processes often lead to the development of adhesions between the reproductive organs. Also, due to frequent pH changes and attacks by immune cells, the internal structure of the uterine mucosa changes, making it very difficult for embryos to implant into it and receive nutrients from it;
• developing in ovarian tissue, inflammation leads to a decrease in follicular reserve.

Abortions and diagnostic curettages in the past

Such manipulations reduce the chance of a positive IVF result at 40 years old due to the following reasons:

• can cause endocrine disorders that interfere with the normal course of pregnancy;
• promote the formation of intrauterine adhesions (synechias);
• can cause isthmic-cervical insufficiency or the development of polyps inside the uterus.

Low follicular reserve

This term means that a woman has few follicles left from which full-fledged eggs can develop, giving rise to pregnancy. With age, the follicular reserve is naturally depleted.

In addition, this condition is aggravated by:

• when the girl initially - due to the difficult course of the mother's pregnancy or its genetic characteristics - received fewer follicles;
• with previous inflammatory pathologies of the ovaries;
• endometriosis;
• pelvioperitonitis;
• chronic intoxications – food and industrial;
• due to operations performed on the appendages;
• when smoking, which causes oxygen deficiency in the ovarian tissue.

The presence of a low follicular reserve is indicated by:

• data from a special, transvaginally performed ultrasound - folliculometry;
• low AMH (anti-Mullerian hormone) blood, which is produced only by follicles less than 8 mm in diameter;
• high FSH (follicle stimulating hormone), produced in the pituitary gland. Its elevated level indicates that the body is trying to “stimulate” the ovaries to accelerate the development of follicles, but does not receive a response from them.

Pathologies of partner spermatogenesis

Most often, women whose husbands are the same age or slightly older want to prepare for IVF after 40 with their eggs.

And age does not have the best effect on the reproductive function of men:

• testosterone levels decrease;
• long-term influence of toxic substances, mainly industrial production (ammonia fumes, pesticides, heavy metals and others), as well as cigarette tar and alcohol, affect the structure of structures responsible for sperm production;
• testicular hypoplasia is also caused by the habit of consuming foods lacking in vitamins E, B, C, A;
• prolonged exposure to an electromagnetic field causes changes in the spermogram;
• permatogenic epithelium also suffers from the effects of infections, which did not always occur in an obvious form during life and were treated.

Thus, the older a man is, the more likely it is that his reproductive cells will be less mobile, will become agglutinated, or will not be able to fertilize an egg.

Severe chronic diseases

Pathologies such as diabetes, arterial hypertension or heart failure, suffered by a woman after 45, make it difficult for her to undergo IVF with her own egg. This is due to the fact that these diseases impair the functioning of blood vessels, including those that provide nutrition to the reproductive organs.

Chances of IVF with your own egg and donor egg

Not only does the number of eggs decrease with age; their quality also suffers. As you remember, these structures are laid before a woman is born, so all the negative influences - toxic products, nicotine, previous diseases, poor blood supply - accumulate.

As a result, eggs lose their ability to fertilize, and the risk of chromosomal abnormalities increases, so the embryo may stop developing at a certain stage. That is why IVF after 40 with one’s own egg is not used for all couples; in 5% of cases an oocyte donor is needed.

Donor eggs are sometimes the only way a woman can get pregnant and carry a child to term. For this purpose, an oocyte is collected from a young and healthy woman, whose menstrual cycle will be synchronized with the cycle of the recipient woman using pharmacological drugs.

How to increase the chances of fertilization with IVF

Due to the decrease in the ability of eggs to fertilize, in order to increase the chances of successful conception, couples after 40 most often use an assisted fertilization method - ICSI (Intracytoplasmic Sperm Injection). In this case, the husband's viable sperm is selected and, under a microscope, using a glass microneedle, is injected into the egg.

If age is combined with low sperm quality, the following may be indicated:

• ICSI IMSI (Intracytoplasmic Injection of Morphologically Normal Spermatozoon): injection of sperm into the oocyte, selected under a microscope providing 6000-fold magnification (with ICSI - 400-fold)
• 2) ICSI PIXIE, when only such sperm is injected into the egg that has been tested for “readiness for fertilization” by being dipped in a solution of hyaluronic acid (this substance is contained in the layer surrounding the oocyte). Those sperm that did not die when interacting with hyaluronate have a low chance that they have DNA abnormalities.

Both of the latter methods, IMSI and pICSI, are also carried out in cases where the previous IVF protocol was unsuccessful or ended in miscarriage, as well as when there is a risk of having a child with chromosomal abnormalities.

PGD ​​of the embryo before transfer

To exclude chromosomal abnormalities, the chance of which increases with age, preimplantation diagnosis (PGD) is used in IVF programs after 40 years of age. This is additional testing of an oocyte fertilized in a test tube, which has already begun the process of division, before it is introduced into the woman's uterus. The same term is used to study an egg even before fertilization, if this woman suffers from a genetic pathology

One cell is taken for analysis at the stage when there are from 4 to 10 such blastomere cells (this is the 5th day of embryo development) and they are still absolutely identical. It is studied under a microscope, and some laboratory tests are performed (fluorescent hybridization, polymerase chain reaction). If no anomalies are found, the embryos are transferred into the uterus on the same or the next day. The time frame for the study is extremely short, since subsequently the embryo will not be able to continue development outside the mother’s body.

Preimplantation diagnosis creates a high probability of having a child without genetic pathologies. It approximately halves the risk of miscarriage and multiple pregnancy, and also adds 10% to the chance of successful embryo implantation.

PGD ​​is possible only within the framework of ICSI and ICSI IMSI. It is carried out in the laboratory, without additional effort on the part of the woman or her husband. It is possible both for couples who planned IVF after 40 with their own egg, and for those who used a donor oocyte.

How long does it take to try IVF to get pregnant?

Despite the efforts of doctors and women themselves, the number of IVF attempts after 40 years increases, and the percentage of success the first time sharply drops, which is associated with many processes, most of which occur in the mother’s body. The number of repeated IVF attempts is determined by a reproductive specialist, based on the specific situation.

Thus, it is now quite possible to give birth to a healthy child after 40 years of age with the help of IVF. The technique has been tested on thousands of patients, but depends on a combination of many organismal factors. The success of IVF can be guaranteed as much as possible only by undergoing a comprehensive examination and good training of both partners.

For a modern woman, the age of 40 is still too far from old age, because modern cosmetic procedures and constant self-care can work wonders. But the birth of a child after 40 years is associated with certain difficulties, because you cannot fool nature. The most favorable period for pregnancy is considered to be the age of 20-35 years, but even if time is lost, the chances of experiencing the joy of motherhood remain. You can achieve your cherished goal naturally, but more often they resort to IVF after 40.

For reproductive technology, age 40 and older is not critical, so positive IVF results at 40 are quite realistic. But to achieve them, you need to put in a little more effort: undergo a thorough and complete diagnosis, select the appropriate protocol option, constantly monitor the patient’s condition, etc. According to statistics, pregnancy occurs on the first attempt after IVF at a young age in 30% of cases; the effectiveness of IVF after 40 years decreases to 9%, although the result depends on many factors and is individual for each woman.

IVF at 40: features of the reproductive system

The low effectiveness of IVF in 40 is due to various reasons. Of great importance is the depletion of the ovarian reserve, which increases with age. According to experts, up to 30 years of age the ovarian reserve is 12%, at 30-35 – 5%, after 40 – 3%. This condition is accompanied by a decrease in the chances of a natural pregnancy, but does not exclude it. To increase the likelihood of having a baby in the event of repeated unsuccessful attempts on your own, it is recommended to perform the IVF procedure after 40.

In addition to a decrease in the supply of eggs, the quality of reproductive gametes also deteriorates with age. Since the oocytes located in the ovaries are laid during the prenatal period, they age along with our body and gradually accumulate genetic defects and other disorders. And to carry out fertilization, high-quality embryos are needed, otherwise there is a high risk of stopping the development of the embryo, fading the pregnancy or miscarriage. The IVF procedure at 40 years of age and older can help overcome these difficulties, since embryologists carefully study the obtained oocytes and use only high-quality sex gametes for fertilization.

The features of the IVF procedure after 40 are still being studied. For a long period, experts have studied the likelihood of having a full-fledged and long-awaited baby as a result of IVF after 40 years of age and older. Studies have shown that the birth rate after IVF up to 39 years of age is 24%, IVF at 40-41 - 15%, at 42-43 - 6.6%, 44 and older - 1.3%.

Therefore, when carrying out IVF after 40 years, donor eggs are often used, which are characterized by high quality, viability and a large supply of nutrients and energy. It is quite difficult to agree to IVF at 40 using donor material. But in this situation, the chances of bearing and giving birth to a healthy child after IVF at 40 increase noticeably, and the probability of pregnancy increases to 60-65%.

IVF protocol options after 40 years

There are several options for IVF protocols, which are selected individually according to indications. It is preferable to perform the IVF procedure at 40 with minimal stimulation or a natural cycle. This allows you to significantly reduce the drug load on the body and reduce the risk of developing adverse complications.

Although it is worth noting that the effectiveness of IVF after 40 using these methods noticeably decreases, since fewer eggs are used during the manipulation. Therefore, the doctor and patient must weigh the pros and cons before choosing a treatment method. You can undergo a preliminary medical examination and choose the appropriate treatment option at the IVF Center clinic in Volgograd.

To increase your chances of getting a positive result with IVF after 40 years of age and older, you must:

• Seek specialized help as early as possible;
• Determine the ovarian reserve and the state of the reproductive system. To do this, an analysis is prescribed for FSH, LH, anti-Mullerian hormone (it affects the quality and quantity of eggs and decreases with age);
• The use of additional treatment methods: assisted hatching - partial or complete removal of the zona pellucida to ensure the release of a formed embryo, preimplantation diagnostics - determination of genetic abnormalities before embryo transfer;
• Responsibly approach the choice of doctor and clinic;
• Identify concomitant somatic pathology and abnormalities in the husband’s spermogram.

Consequences for a woman with IVF after 40 years

At the age of 40, a woman’s fertility decreases not only, but also her ability to bear and give birth to a baby, and most patients have concomitant somatic pathology. Therefore, performing IVF after 40 years is associated with some consequences that can adversely affect a woman’s health:

• Hormonal disorders: IVF after 40 years is performed after hormonal stimulation of the ovaries, aimed at producing more eggs. But besides this, medications cause endocrine disruption, which are tolerated differently by women;
• Risk of multiple pregnancies: IVF at any age is associated with the risk of developing multiple pregnancies, but after 40 years, the likelihood of carrying several babies and giving birth to them decreases, and the course of pregnancy may become more complicated and serious health problems may arise;
• Miscarriage: the frequency of miscarriages with IVF after 40 years is noticeably higher than with IVF at a younger age;
• High risk of developing genetic abnormalities: oocytes after 40 years of age are of low quality and accumulate various defects, this can lead to intrauterine malformations. To prevent the risk of developing such a complication during IVF after 40, preimplantation diagnostics are used, as well as constant monitoring of the condition of the woman and child;
• Formation of placental insufficiency: by the age of 40, the condition of the uterus worsens in most patients as a result of various gynecological diseases and inflammatory processes. All this can cause improper attachment of the placenta, as well as placental insufficiency during IVF after 40 years, which reduces the blood supply and nutrition of the embryo, increasing the risks of developmental abnormalities;
• Severe pregnancy: at the age of 40, many women have developed chronic somatic pathology, which can worsen the course of pregnancy after IVF. In addition, there are known cases of the occurrence and exacerbation of diseases during IVF after 40 years. They worsen the course of pregnancy, adversely affecting the condition of the body of the woman and the baby.

It is worth noting that the risk of developing complications with IVF after 40 years can be reduced through a full-fledged medical examination, the choice of a qualified and experienced doctor, compliance with the recommendations of a specialist, as well as constant monitoring of health status both on your part and on the part of the doctor. Age is not an obstacle to the birth of a baby; if you approach therapy with all responsibility, you can achieve your cherished goal.

Treatment methods for female and male infertility are constantly being improved, thereby gradually expanding the age limits of patients who are able to bear and give birth to a child. Now successful IVF after 40 years has become a reality.

Reviews of successful cases of conception and pregnancy at this age have long become not isolated, but widespread. Experts identify certain periods of a woman’s reproductive age – 12-55 years. The most favorable period for conceiving and bearing a baby is 20-35 years, but in recent years cases of late pregnancy have become more frequent.

Not so long ago, a girl who gave birth for the first time at the age of 25 was called an old-timer. Now many people think about having a child only after 30 or even 40 years old. Sometimes the reason for such a delay in motherhood is concern for a career or the lack of a suitable man nearby. Quite often, women decide to become pregnant and give birth at a late reproductive age out of a desire to have children together in their second marriage. Having failed to conceive a child naturally, they resort to the IVF procedure, because after 45 years, judging by the reviews of doctors, the ability to conceive is seriously reduced. In addition, at this age, the number of viable eggs sharply decreases, and men also contribute to problems in the reproductive health of the couple.

Causes of infertility in women of late reproductive age

For women after 35 years of age, the inability to conceive a child naturally within 6 months requires contacting a fertility specialist, since after 37 years of age, fertility declines sharply. The ovarian reserve (the number of healthy eggs) is depleted and the chances of pregnancy are reduced, even with the help of assisted reproductive technologies. In addition, the aging uterus has less and less ability to hold the embryo, and the number of chromosomal abnormalities is increasing.

According to statistics, only 50% of women after 40 years of age can become pregnant naturally; the chances of successful conception after IVF at 40 years of age and older are much higher. Although, if we compare the effectiveness of IVF procedures at an early age and IVF after 40, then approximately 9% of protocols end in success. It is worth noting that the effectiveness of the IVF protocol at 40 years of age increases with the use of donor materials.

However, all these indicators are relative and the health of each woman has its own individual characteristics. An adult woman who feels great and wants to have a child can easily have offspring with the help of IVF even after 45 years, and numerous reviews on forums are further confirmation of this. Modern scientific methods can work wonders even for women after the onset of menopause, because each case requires an individual approach. That is why IVF after 40 years, reviews of which can be found on the website of the IVF Center reproductive clinic, is a solution that can bring success. Everything depends only on the individual abilities of the woman’s body.

Difficulties with IVF after 40 years and older

• Depleted ovarian reserve: it is worth noting that not only the number of maturing follicles during 1 cycle is taken into account, but also the quality of the eggs obtained. After all, the germ cells are often damaged or altered, so there is no possibility of conception and durable implantation;
• Hormone levels: a woman’s hormonal levels change at the end of her reproductive period, which can affect pregnancy, its course and childbirth;
• The risks of genetic abnormalities are high: when IVF is performed after 40, the risk of congenital pathology increases by 20%. That is why it is advisable to resort not to natural pregnancy, but to IVF at the age of 40, since the latest diagnostic methods make it possible to assess the quality of the resulting embryos and the degree of possible deviations. Based on the results, embryos of suitable quality are implanted.

Complications after successful IVF at 40 years of age and older

Performing successful IVF after 40 years is associated with certain difficulties for the expectant mother:

• Hormonal changes: the IVF protocol after 40 and others use stimulation of the ovaries with hormonal agents, this can cause serious changes in the woman’s body. At an early age, all deviations are perceived more easily;
• Multiple pregnancy: when performing IVF after 40 and other cases, specialists transfer 2 or more embryos; carrying several fetuses can negatively affect the woman’s condition;
• High risk of miscarriage: multiple pregnancy with IVF after 40 significantly increases the risk of miscarriage, critical periods are 20-22 weeks and 26-28 weeks;
• Placental insufficiency: IVF after 40 years can lead to placental insufficiency, since the condition of the uterus deteriorates by this age, this can cause fetal hypoxia, its death and the development of serious health problems;
• Difficult pregnancy: IVF at 40 years old can result in pregnancy, but this often causes exacerbation of somatic diseases, and the general condition of systems and organs may be unsatisfactory.

IVF after 35 years. Reviews and features

For any assisted reproductive technology, the age of the patient matters, because the chances of successfully conceiving a child even with the help of IVF after 40 years, judging by reviews from doctors, are significantly lower than for women after 35 years. So, after forty, only 5-10% of fertilization attempts are successful. In addition, the incidence of miscarriage increases. If the patient’s supply of eggs has dried up, donor eggs can be used, which provide a higher chance of pregnancy.

Modern assisted reproductive technologies help to become a mother with the help of IVF after 35 years, but reviews from patients indicate that it is not worth postponing the birth of a child for a long period. If you have the slightest suspicion of infertility, you should visit a doctor.

Should I do IVF after 40 years? No reproductive specialist can give a definite answer to this question. On the one hand, there are no official prohibitions on the use of assisted reproductive techniques for women after 40 years of age. The legislation of the Russian Federation does not impose age restrictions on the use of the IVF protocol in patients. This means that in the absence of contraindications to artificial insemination, a woman of any age can undergo the IVF procedure. On the other hand, the list of these very contraindications to undergoing IVF at an older reproductive age is significant, since the body of a woman at 40 years old is different from the body of a young girl.

Successful IVF after 40 years is not uncommon, however, a positive result of the procedure can only be achieved if there are no contraindications to bearing a child and the presence of germ cells of the proper quality on both the woman’s and the man’s part. Doctor Lazarev A.P. and his team, consisting of experienced reproductive specialists, are always ready to select the optimal in vitro fertilization protocol for patients of any age and with any characteristics.

Conditions for IVF after 40 years

Why are there special requirements for IVF after 40 years? Because this age is critical for the female reproductive system. The supply of eggs after 40 years is minimal, and some people already reach menopause at this age. The natural process of aging of the ovaries and age-related changes in the functioning of the gonads significantly reduce the likelihood of fertilization and successful pregnancy. Only 5-10% of patients manage to get pregnant during IVF the first time after 40 years.

By the age of 40, a woman acquires various chronic diseases, and the supply and quality of her eggs, on the contrary, become lower. If the eggs have aged, most likely the genetic material in them is damaged. Using such eggs for fertilization increases the risk of genetic abnormalities in the child, as well as the likelihood of miscarriage. Among other things, the number of eggs suitable for fertilization may simply run out after 40 years. That is why successful IVF at 40 years of age is only possible if certain conditions are met.

• Sufficient supply of eggs. If you want to undergo IVF with your eggs, the patient must have enough oocytes - germ cells that can transform into mature eggs ready for fertilization. You can find out your egg supply by undergoing an ultrasound examination or taking a hormone test.
• The absence of somatic diseases that interfere with the normal course of pregnancy. Serious diseases of the kidneys, heart and endocrine system reduce the chance of successful implantation of the embryo and the development of pregnancy in the future. It is necessary to exclude factors that influence possible miscarriage, which is common in older pregnancies, as well as severe pregnancy and the development of placental insufficiency.
• Possibility of hormonal therapy. Stimulating the maturation of several eggs is an important stage of the artificial insemination procedure. Contraindications to hormonal therapy or ineffective stimulation of superovulation reduce the number of embryos obtained during IVF. The doctor determines the effectiveness of hormonal therapy based on examination data.
• The partner's sperm is of proper quality. When undergoing IVF in adulthood, the good quality of not only female but also male germ cells is important. The suitability of a man's sperm for fertilization is determined by an analysis called a spermogram.

Features of the IVF procedure after 40 years

Patients who decide to have successful IVF after 40 years of age should be prepared for an extensive examination. In addition to the usual types of diagnostics required before in vitro fertilization, additional types of examination may be needed.

• Follicle counting
  Assessment of ovarian reserve using transvaginal ultrasound is very important for age-related IVF. By counting the follicles, the specialist can predict the chances of success of ovarian stimulation and obtaining healthy eggs.
• Blood test for hormones
  When conducting IVF after 40 years, doctors pay special attention to the level of the hormones FSH and progesterone. The lower the level of follicle-stimulating hormone, the more eggs the expectant mother has in stock. A sufficient level of eggs is fixed when the FSH concentration is 10 IU/ml or lower.
• Preimplantation genetic diagnosis
  Those who have done IVF at the age of 40 know that technically the artificial insemination procedure is no different from IVF at a young age, except that the number of eggs obtained may be less. However, in some cases, additional manipulations, such as preimplantation diagnostics, may be necessary before egg fertilization. This technique allows you to select only healthy eggs for fertilization, excluding germ cells with genetic abnormalities.

IVF at 40 with a donor egg

Often, successful IVF after 45 years is only possible using donor eggs. If the body no longer produces its own eggs or the reproductive cells are of poor quality, have genetic abnormalities and are unsuitable for fertilization, a woman can still undergo IVF, carry and give birth to a baby. To do this, she will be asked to select an egg donor from the database.

IVF with DU after 40 years brings a positive result much more often than IVF with one’s own eggs of average and low quality. This type of artificial insemination does not involve hormonal stimulation of the ovaries. At the desired phase of the cycle, the patient is transplanted with donor eggs fertilized with her husband's sperm. Pregnancy after IVF with donor material is observed as usual. The effectiveness of IVF after 40 years

For patients aged 40 years, IVF the first time and with a positive result is a rare occurrence. The chances that artificial insemination will be effective the first time are only a few percent. But young patients often have to undergo IVF several times before achieving the long-awaited pregnancy. This is a normal practice for IVF at 40 years old - who succeeded and who didn’t, doctors cannot predict the result of the procedure. Many patients ask: if you do IVF at the age of 40, at what point should you wait for the result? Most often, in this case, women become pregnant on the second or third try. If this does not happen, do not despair. There is always the option of trying IVF with a donor egg; this procedure is much more effective than IVF with your own low-quality oocytes.

Doctor Lazarev A.P. works with patients of any age, regardless of their health characteristics. For patients over 40 years of age, an individual effective program of examination and IVF is always developed. If it is necessary to undergo IVF with donor eggs, a woman will be offered a database of healthy, verified donors and assistance in choosing. Successful IVF after 40 years is quite possible.

Our clinic will be happy to give you hope for long-awaited motherhood using the in vitro fertilization method (IVF method), which has been successfully used by specialists at our clinic for several years.

When contacting patients, the question arises: what is the likelihood of pregnancy in this particular case? In most cases, the answer is: there is a chance of getting pregnant, but the effectiveness of the method is approximately 15-20%, while in women under 35 years of age it is 40% or higher. Most often, for patients over 40 years of age, use with or without (without) is recommended as the most effective.

This is a new direction in the treatment of infertility, which has given hope for the birth of a baby to many couples. This procedure has become possible in the late reproductive period. In this case, the doctor informs the patient about the possibility of using a donor egg. As a rule, donor programs are quite effective.

IVF after 40 years is possible if:

A woman has no contraindications for conceiving and carrying a pregnancy from the reproductive system;

There are no contraindications for hormone therapy. This is due to the fact that upon the onset of menopause, the hormonal background of the female body changes, which can affect the course of the first trimester of pregnancy;

Absence of any somatic diseases (internal organs, heart). The conclusion is issued by related specialists.

These are the main indicators, however, it is possible to determine the possibility of using the IVF method in your case only after a complete examination of the body.

What examinations are necessary to undergo for successful use of the IVF method in the late reproductive period?

Before IVF, our clinic’s specialists will examine your body and give their opinion on the feasibility of this method. There is a list of studies in accordance with Order No. 107 of the Ministry of Health of the Russian Federation, which includes:

Ultrasound of the pelvic organs in order to exclude the inflammatory process is performed more often in the first phase of the menstrual cycle (5-7 days);

The range of necessary laboratory tests for blood, urine, and patient tests;

Study of hormonal blood profile;

Genetic screening-karyotyping;

Consultation, ECG, FLG.

IVF is a shared responsibility of both the mother and father of the unborn baby. To determine the most effective set of procedures, it is necessary to conduct studies on the fertilizing ability of sperm.

The experience of our clinic confidently shows that a woman aged 40 to 50 years can become the mother of a healthy child, and we will be happy to help you with this.