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From test tube to birth: How and why IVF is done. Test tube baby: myths and truth about IVF How much does it cost and who pays

Today, July 25, is the 40th birthday of Louise Brown, the English nanny who became the world's first test-tube baby. The first person in the world to be born as a result of artificial insemination (IVF) is alive and well today, Louise is a happy wife and mother of two sons conceived naturally.

Over the years, assisted reproductive technologies have changed a lot, and sometimes doctors manage to do the impossible: in Russia alone, over the past decades, more than 1 million children have been born using in vitro fertilization (IVF).

Today, reproductive doctors, thanks to IVF, help not only infertile couples to find happiness in becoming parents, but also people who want to preserve germ cells for future use (delayed motherhood programs), patients with cancer before heavy chemotherapy that kills germ cells, so that after If cured, they could have children.

IVF helps couples who do not suffer from infertility, but have hereditary genetic diseases, to give birth to a healthy child. The successes of reproductive specialists are impressive, however, there are a lot of myths and prejudices around IVF. Gynecologist-reproductologist Yulia Tsoraeva debunks the main myths about IVF.

Myth 1: Taking oral contraceptives can reduce and slow down the consumption of eggs and, thus, increase a woman’s chances of a late pregnancy.

It is impossible to slow down the biological process of maturation and release of eggs. There is such a thing as follicular atresia - the reverse development of follicles in the ovary: the follicles are genetically programmed to die.

Normally, with or without taking contraceptives, one follicle matures in the female ovary every month and ovulation occurs, the remaining 10 next to it die. And so on every month. When taking contraceptives, ovulation does not occur, but the follicles still rise, fertilization and division do not occur, and they become atretic - they die.

Myth No. 2: You can search for your prince for a long time, sort through candidates, pursue a career and give birth after 35-40; modern medicine allows you to postpone motherhood to a later date. It doesn’t matter that the number of follicles decreases in the female body, the main thing is that the woman has good genetics.

The female body produces a sufficient number of genetically healthy eggs to give birth to a healthy child only up to a certain age, as nature intended. There are no strict age limits here; for some, even before the age of 30, all eggs will be genetically defective and will not produce healthy offspring. But most doctors believe that you should still give birth to your first child before the age of 35. Let's explain why.

In a woman under 35, out of 10 eggs, seven will be healthy, from which three healthy embryos can be obtained during fertilization. In a woman aged 35 to 40 years, out of 10 eggs, only 5 will be healthy, from which 2-3 embryos can be obtained. After 40 years, the number of healthy eggs falls catastrophically: at 40, only 10% of eggs remain high-quality and suitable for fertilization, at 42, even less - 5%.

In order to get a healthy egg and a healthy embryo at 42 years old, a woman needs to take 18 (!) high-quality eggs, but at 42 years old they simply don’t exist. Of course, doctors are trying to help women over 40-45 years old to give birth, but working with genetics is not easy: chromosome division is disrupted with age, and one of the most dangerous pathologies is the incorrect divergence of the 21st chromosome, which causes Down's disease.

Myth No. 3: After IVF, a woman’s risk of developing cancer greatly increases.

This is a misconception; the procedure for stimulating the female reproductive system does not increase the risk of developing cancer. There is no scientific data to support this. This opinion was formed due to the fact that patients in reproductive clinics are examined much deeper and more extensively than in any other clinic, and thanks to additional research, cancer can be detected at an early stage, which has not yet manifested itself.

If an ultrasound reveals some small pathology, for example, a small lump in the breast, the woman must undergo a mammogram to exclude the diagnosis of breast cancer. If the patient has a history of chronic gastritis, she will definitely be referred for a consultation with a gastroenterologist and undergo a gastroscopy to make sure that she does not have a malignant process in the digestive organs.

All this is done in order to exclude any complications and identify hidden health problems, if a woman has any. The more frequent detection of cancer among women who are preparing for the IVF procedure, or who have already had IVF, is only due to the fact that we examine our patients more thoroughly.

Myth No. 4: Children conceived through IVF are more often born with congenital pathologies and various diseases, including mental disorders and diseases of the nervous system.

This is a myth, because we, on the contrary, help embryos, which are indeed not always genetically healthy, to take root. The embryo receives more hormones, more nutrients and, even if it is genetically unhealthy, is helped to survive.

But with IVF there is a greater number of premature births, this is indeed true: if 60-70% of transplanted embryos take root, then much less reach birth.

Today there are methods that can reduce the frequency of chromosomal abnormalities in the embryo, but they cannot be completely eliminated. As with natural fertilization, sick children are born without IVF, and the woman is not always “to blame” for this.

Male factor accounts for approximately 40% of all cases of infertility, a man's fertility can be greatly reduced by sexual, hormonal problems (thyroid disease, pituitary tumors, low testosterone), problems related to the quantity and quality of sperm (for example, low sperm motility).

Myth No. 5: Immediately after transferring embryos into the uterus, a woman needs strict bed rest for the embryos to take root.

There is no need for this; moreover, the woman must move. Whether the embryo takes root or not strongly depends on the blood flow in the uterus: the more intense the blood flow, the better the nutrition of the organ; nutrients are supplied to the embryo with the blood flow. When a woman lies down, blood circulation in the pelvis decreases sharply, and blood clots form much more often.

If my patients are lying down and are afraid to move, I tell them: “You can lie down, but be sure to move your legs, do some simple exercises, and under no circumstances lie or sit cross-legged in a cross-legged position.” Normal physical activity should be the same as during natural fertilization.

Myth #6: Doctors have no control over the success of IVF and cannot guarantee a positive result.

The effectiveness of IVF, that is, data that shows how many women after the stimulation procedure will become pregnant, carry and give birth to a child - the numbers are very subjective, it all depends on the age of the women. Before the age of 30, 70-80% of patients become pregnant on the first try and carry the baby to term; after 35 years, the percentage of pregnancy and pregnancy is lower; after 40 years, it is even lower.

If a woman fails to get pregnant on the first try, the doctors’ task is to find out the reason for the failure so that the subsequent attempt at artificial insemination will be successful. But I repeat: the younger the woman, the higher her chances of getting pregnant. The effectiveness of IVF at 40-41 years old is only 5-7%. For such women, there is the next stage - donation or surrogacy.

The number of infertile couples is growing, doctors attribute this to poor ecology, a very high pace of life, chronic stress, poor nutrition and many other factors, among which one of the most problematic is postponing pregnancy to a later date. Young women are busy with their studies, careers, self-realization, and travel actively, preferring to postpone having a child “for later.”

And forgetting or simply not thinking about the fact that with age the probability of having a healthy child decreases - simply because this is how the female body works: according to the laws of nature, a woman should give birth for the first time at a young age - up to 30 years. But doctors are observing an increase in the average age of women planning to give birth to their first child: increasingly, beautiful ladies aged 45-50 who want to become mothers naturally, which is practically impossible, turn to reproductive specialists.

On the test tube ru forum you can exchange opinions about in vitro fertilization, other methods of infertility treatment and preimplantation genetic diagnosis, and leave your feedback on the infertility treatment performed.

At the forum, they will tell you in clear language how test tube babies are born, what reproductive medicine is, and what methods modern medicine offers for artificial insemination in case of male or female infertility. If you are interested in how sperm cryopreservation, egg and embryo preservation works, then the forum is the ideal place to get answers to such questions. By showing the results of a spermogram or blood test on the Test Tube forum, you can get a comprehensive consultation.

Test tube babies: important details in detail

The forum brings together a huge number of people and provides them with an open platform for communication.

By communicating on this Internet resource on such topics as an IVF clinic, how to prepare for in vitro fertilization, what infertility treatment methods are offered by one or another reproductive medicine center, where to find a sperm bank and an egg donor, “eco-girls” acquire a lot of useful information and get acquainted with people who have gone through all stages of IVF and can give practical advice.

In addition, Probirka.ru is a place where you can ask for reviews about a particular clinic or specialist. Virtual acquaintances sometimes develop into real connections. It happens that people begin to become friends with families. Often, friendly relations arise between professional doctors who practice IVF and “eco-forum members”.

Often, test tube babies become the result of information exchange between forum members on probirka.org.

A participant in the “ekoshnits” forum (“Test Tube” forum) receives here the latest data on human reproduction, changes and improvements in IVF techniques, and advice from practicing doctors.

Public opinion is largely formed through dialogue between potential patients and clinic specialists. A large number of people are interested in the possibility of participating in the IVF program, receiving detailed consultations related to conceiving a child, sperm and egg donation. Test tube is an IVF forum where you can find answers to almost any question regarding artificial insemination.

Popular Topics

Popular topics on the probirka.org forum:

  • How to get pregnant
  • Conceiving a child
  • Planning for children
  • Male infertility
  • Female infertility
  • Sperm donor
  • Egg donor
  • Infertility tests
  • Spermogram

Forum visitors communicate little about such issues in their daily lives. They believe that this information is private and sharing it publicly could harm their reputation or social status.

Not every person can dare to ask a question directly; on Probirka.ru you can get an answer to any question without fear of misunderstanding or ridicule. On the forum pages, communication occurs anonymously. That's why people feel relaxed and safe here.

Sometimes the patient does not get a positive result from the IVF procedure the first time. He has psycho-emotional problems that are difficult to solve when he is alone with his thoughts.

Believe in success and communicate on the Test Tube forum

For those who want to communicate, the site’s creators have organized a forum on Probirka.ru. Friends, this section is intended for free communication on all topics related to IVF, infertility and methods of its treatment.

We will facilitate any dialogue between interested parties and ask visitors to Probirka.ru (forum) to be mutually polite and tactful, not to use offensive expressions and threats in correspondence, and to avoid obscene language and flooding.

We draw special attention to the fact that communication on the forum occurs only between visitors to this Internet resource. If you need to get advice from a specialist or ask a question to a doctor, you should use the “Ask a Doctor a Question” section.

Test tube babies are a miracle that modern medicine can perform. All you need is a great desire and a good clinic.

In 2001, when modern technologies for treating infertility came to Moscow, the Clinic for Assisted Reproductive Technologies “Test Tube Babies” opened.

The most famous doctor in Russia, Emma Vramovna Vartanyan, becomes its leader.

Together with her, experienced reproductive specialists who previously worked at the 20th Clinical Hospital stood at the origins. Later, the institution became a multidisciplinary center, which is visited by those who dream of having healthy children, experiencing problems with conception.

Location

The reproductive medicine clinic is located in the North-Western Administrative District of Moscow.

The private institution is open at the address: Shchukinskaya street, 2 (Shchukino district).

Main activities

“Test Tube Babies” is a specialized center that uses effective artificial insemination techniques to treat infertility.

Specialists successfully use in vitro fertilization, vitrification technology for cryopreservation, IVF, ICSI and other methods of reproductive medicine.

Services provided by the clinic

The clinic provides most services for a fee. Compulsory medical insurance procedures are possible.

The institution, equipped with sophisticated equipment, offers:

  1. treatment ;
  2. modern diagnostic methods (endometrial biopsy, and others);
  3. , GIFT, ICSI, MESA, ZIFT, TESE, insemination and other ART;
  4. pregnancy management;
  5. course of therapy during menopause;
  6. specialist consultations;
  7. storage of genetic material in a cryobank;
  8. surrogacy;
  9. donor programs.

IVF programs

Spermatozoa and embryos are subject to storage with pre-treatment with a cryoprotector. The clinic has introduced a rapid freezing method (vitrification).

Analyzes

Qualitative research of the material is carried out in the laboratory. Patients undergo blood tests, check the quality of sperm, undergo tests for hormones, and the presence of sexually transmitted diseases.

It is possible to undergo a coagulogram, postcoital test, and other specific studies to identify factors of infertility.

Specialists

The clinic’s specialists are ready to offer complex treatment and solutions to any problem caused by infertility.

Obstetricians, reproductive specialists, geneticists, gynecologists, andrologists, endocrinologists, therapists, and embryologists work with patients.

Video: Series of programs with E.V. Vartanyan. Infertility and its causes

Olga Lukinskaya

Infertility is a difficult diagnosis, which can have a variety of reasons. If a couple wants a child, but pregnancy does not occur, there are several options, the choice of which depends on the specific characteristics of the partner’s body, financial capabilities, and personal preferences: apply for adoption, use the services of a surrogate mother, try to achieve pregnancy with the help of in vitro fertilization (IVF) procedures. Everyone has heard about the latter, but many are still not sure how it actually happens. We talked with Tatyana Verkhovnikova, a fertility doctor at the Mother and Child clinic in St. Petersburg, and asked about the IVF experience of women who have gone through it.


How to prepare for IVF

Preparation is, first of all, an examination, which is carried out according to a certain scheme (in Russia it is determined by Order of the Ministry of Health No. 107n). The purpose of the examination is to understand whether IVF is indicated and whether the pregnancy will be safe for the patient. The couple donates blood, tests for infections are performed, and the man undergoes a spermogram. The woman is also tested for hormones to identify diseases that may interfere with pregnancy - for example, problems with the thyroid gland. The level of the so-called anti-Mullerian hormone is determined, which helps to understand how many eggs are left in the ovaries and predict how many of them can be obtained.

General blood and urine tests are also done, an ECG and fluorography are performed, a consultation with a therapist is scheduled, the woman must undergo a breast examination - stimulation with hormonal drugs can affect their condition. Sometimes consultations with other specialists are needed to obtain their permission and recommendations. If the examination reveals any violations, it may take several months to correct them. In addition, since the goal of IVF is pregnancy, the couple must follow general recommendations for a healthy lifestyle: be active, get enough sleep, do not smoke and give up alcohol, eat a balanced diet; the woman should start taking folic acid three months before the procedure.

How eggs are collected and fertilized

IVF is a team effort between the patient, reproductologist and embryologist. From the first day of the menstrual cycle, a woman begins hormonal medications to help mature a larger number of eggs than usual. These medications are selected individually by a reproductologist; They are administered in the form of injections, subcutaneously (in the abdominal area) or intramuscularly - in the latter case, the injections bring quite noticeable discomfort. Ovules are developing inside the ovary in follicles - structures like vesicles filled with fluid (under natural conditions, the follicle ruptures at a certain moment, releasing the egg - this is called ovulation). Stimulation with hormones lasts ten to twelve days, during which ultrasound is done two to three times to assess the growth of follicles and adjust the dosage of the drug. In the middle of the menstrual cycle, when the follicles have grown to a certain size, the last injection is given to ensure that the eggs mature, and the puncture day is set for when they will finally be extracted.

Egg retrieval is usually performed under general anesthesia (anesthesia); Each follicle is pierced with a thin needle, and the collected liquid is transferred to the laboratory, where embryologists look for eggs in it under a microscope. On the same day, the man donates sperm, in which the same embryologists identify motile sperm. The patient goes home, and embryologists begin to fertilize the resulting eggs. If there are a lot of motile sperm, then conventional in vitro fertilization is performed: sperm and eggs are left in the same cup with a nutrient medium in an incubator for sixteen to eighteen hours and fertilization occurs there in the same way as in the uterus. But if there are few motile sperm or they are of poor quality, then the ICSI procedure (intracytoplasmic sperm injection, ICSI) is performed. In this case, the embryologist uses a microneedle under a microscope to inject sperm into each egg and leave them in the incubator; sperm are selected based on the absence of abnormalities in their structure and normal motility.

Anastasia Aksyanova

The puncture lasts about half an hour, is done under anesthesia, under ultrasound control. I tolerated everything very easily, there were no side effects. Then, however, for several days there was discomfort in one of the ovaries - more eggs were taken from there. On the same day, sperm was taken from my husband and fertilization was performed.

How embryos are transferred

On the next day after fertilization and in the following days, the embryologist evaluates the fertilized egg (from the fifth day it is called a blastocyst); this looks at the inner cells that will become the fetus, the outer layer of cells that will become the placenta, and the cavity between them. There are criteria (what these cells should be and how many there should be) that help determine the “quality” of the embryo, that is, its viability and development prospects. It often happens that processes do not go as desired, and some embryos do not develop - that is why during stimulation it is important to obtain not just one egg, but several, so that there is a choice. For the next three to five days, the embryos grow in a nutrient medium, and their condition is assessed every day by a specialist.

One or two embryos that meet medical criteria are then selected and transferred into the uterine cavity. This procedure does not require anesthesia; the patient sits in a regular gynecological chair, and the embryos are transferred into the uterine cavity through the vagina using a tube (catheter). Finally, two weeks after this, the patient takes a pregnancy test (usually a blood test because it is more reliable than a urine test).

According to Verkhovnikova, now that reproductology and embryology have reached a higher level, IVF results in more embryos with the prospect of engraftment and growth - and the transfer of several embryos quite often leads to multiple pregnancies. Pregnancy itself with more than one child is considered complicated: such pregnancies are more often interrupted or end in premature birth, which is dangerous for both the mother and children. Since this is at odds with the very idea of ​​IVF, intended to give birth to a healthy child and preserve the woman’s health, recently only one embryo is being transferred more and more often. The rest can be frozen and stored in a special bank of biomaterial; storage can cost about 35 thousand rubles over ten years. In the future, the couple can return to the clinic and use one of their own embryos for a second pregnancy - or sign a consent form. Unfortunately, not all embryos survive thawing either - about 15% lose viability.

Anastasia Aksyanova

First, they transferred one embryo to me, but it did not take root - it turned out that the endometrium (the inner layer of the uterus) was not ready for pregnancy. I was reassured by the thought that there were two more embryos stored in the freezer, but the endometrium needed to be prepared. To do this, I took medications for several more months and smeared my stomach with a special ointment. This went on from about April to August and finally I successfully transferred two embryos. The procedure does not cause any discomfort: you lie in a chair, and the embryos are injected with a large syringe with a long tube.

A few days later, one of the embryos split in two - I remember how a hormonal wave covered me at that moment. Of course, when the doctors saw the triplets, they suggested that I do a reduction, that is, remove one embryo - this is a standard procedure, this is the first thing they talk about. Multiple pregnancies are generally risky, both for the children and for the mother, and with identical twins the risks are even higher. But we still decided not to reduce anything, and now ours is already two years old.


How often do failures happen?

A reproductive specialist notes that the likelihood of pregnancy after IVF depends on age. Eggs are laid at birth, and new ones do not appear during life, but are only wasted; Unfortunately, sperm quality also decreases with age. If the probability of becoming pregnant using their own eggs in women under thirty-five years of age is more than 30%, then after forty-five years of age the chances drop sharply. It is clear that even with the best chances, pregnancy may not occur on the first try. On average, a young couple needs three IVF attempts to become pregnant, although everything can work out the first time.

Vera Nekrasova

I was implanted with one embryo, and it did not take root. The easiest way is when several embryos are transplanted on the third day and they wait for at least one to take root. But there is a risk of multiple pregnancy. Therefore, we took the path of growing embryos until the fifth day and transferring one of them. This was the most terrible stage: on the fifth day it turned out that out of nine embryos there were five left, and all of them were not very viable. The doctors decided that they wanted to keep an eye on them, so they didn’t have time to transplant anything to me this cycle. Two days later, only two embryos with IV quality were frozen (in the embryo quality classification, the letters A, B and C evaluate two different parameters, and A means the most favorable option; that is, the best prospects will be for embryos rated as AA, and then AB. - Ed.). The transfer was done in the next cycle, and there was still a chance that the embryo would not survive the defrosting, but everything went well. But in the end, pregnancy still did not occur.

It was very difficult, because all this takes place under a hellish dose of hormones, you constantly feel bad. In addition, some of the medications that I had to inject had terrible possible side effects described in the instructions - this also did not add joy. I also had a very bad time with the egg retrieval itself; I recovered from anesthesia for two days ( Typical side effects of anesthesia include drowsiness, confusion, and memory impairment. - Approx. ed.). We decided not to try again - I am alone and would not want my physical or mental health to deteriorate because of the illusory possibility of conceiving on the tenth attempt.

Why everything is like this - no one knows. Perhaps we simply do not have very useful genes for reproduction, and therefore, even with IVF, embryos are not viable. In general, the idea of ​​adoption is more organic for me, and if it were not as difficult as it is now, then I would not think about IVF. I’m not ready to go through such a load again - it took me about a year to come to my senses.

How much does it cost and who pays

The cost of IVF in Russia is from one hundred to three hundred thousand rubles, and it depends on how many hormonal drugs are needed, what procedures will be needed (ICSI, genetic screening of embryos - it is used to exclude dangerous genetic diseases, especially if their risk is increased, for example, they were or are in close relatives), whether donor material is used (eggs or sperm). True, not everyone knows that compulsory health insurance covers IVF, that is, it makes it possible to do it for free. To do this, you need to undergo an examination in accordance with Order No. 107n and collect a package of documents; the patient can choose the clinic where she would like to have IVF.

According to Verkhovnikova, the queue in Russia for free infertility treatment is very short - in other countries like the UK, France or Spain it can take several years, and in the USA there are no free IVF programs at all.

Anastasia Aksyanova

We used to live in Vladimir, and I knew people who did IVF under compulsory medical insurance. They had to wait a year or more. Already in Moscow, when we decided to do this, I wanted to do everything in a certain center; There was money at that time, so we decided not to wait for any quotas, but to apply there. The entire IVF protocol with medications cost us about one hundred and twenty thousand rubles. Then, when it turned out that I had triplets, I turned to a very good specialist for pregnancy management - she is a Doctor of Science and specializes in multiple pregnancies. In the end, everything together, from preparation for IVF to childbirth, cost about three hundred and thirty thousand.

Why IVF sometimes “cures” infertility

Conceiving a child by artificial insemination has long passed from the category of amazing events to an almost ordinary phenomenon. Every year more and more IVF centers appear, and their services are becoming more in demand and accessible.

Every childless couple diagnosed with infertility, looking for their own IVF medical center, is faced with the problem of choice. It is worth noting that there is no single and comprehensive rating of IVF clinics that one could rely on. On thematic websites and forums you can find attempts to rank fertility centers by their clients and some medical experts, but such ratings are more often based on an emotional assessment, and less often on an impartial approach. Nevertheless, there are objective indicators of the reliability of a medical institution and the quality of services provided. Let's try to formulate our rating of IVF centers based on several important criteria.

What distinguishes a good IVF center from a bad one?

The best IVF clinics have a number of important features that you should pay attention to first:

  • Professionalism of doctors . The best IVF centers employ experienced reproductive specialists, embryologists, and andrologists who are members of such respected organizations as the Russian Association of Human Reproduction (RAHR), the American Society for Reproductive Medicine (ASRM), and the European Society of Human Reproduction and Embryology (ESHRE).
  • Treatment effectiveness . The most important indicator in the rating of IVF centers is the percentage of positive outcomes of infertility treatment using ART.
  • Availability of own laboratories and cryobank . The best IVF centers have the latest equipment and materials to provide a full range of laboratory and instrumental tests.
  • Multifunctional medical care . It is convenient when the clinic’s staff includes a therapist, surgeon, mammologist and other specialized specialists.
  • Comfortable conditions stay in a clinic or hospital.
  • Possibility of processing medical documents - sick leaves, exchange cards for pregnant women.

To assess the reliability of a clinic, you should carefully study its official website, reviews of the clinic and specialists on third-party resources. It is also worth paying attention to what types of activities the IVF clinic has valid licenses and certificates for.

Trusted medical centers in Moscow

Today, the list of IVF clinics in Moscow includes about 70 institutions. It contains the largest public clinics - the founders of IVF in our country, as well as private centers - large networks with branches in many regions and “chamber” fertility centers created relatively recently. All of them are distinguished by both the list of implemented ART programs (from 5 to more than 20) and the range of prices for services (see table).

Now we will take a closer look at several of the most famous and reputable IVF clinics, which can safely be included in the list of the best.

"Embryon": medical center for the treatment of infertility

One of the first clinics in the Russian Federation to provide ART services. Founded in 1992. The permanent director and founder of the clinic, Candidate of Medical Sciences Kim Nodarovich Kechiyan, has extensive experience in the field of IVF (more than 40 thousand IVF cycles since 1987), and is one of the few heads of clinics who are involved in practical work on a daily basis. He is directly involved in the provision of in vitro fertilization of oocytes services as an attending fertility specialist and embryologist. Kechiyan Kim Nodarovich was awarded the Prize of the Government of the Russian Federation for the introduction of IVF into clinical practice.

As for the clinic itself, Embryon has a close-knit team of employees: highly qualified reproductive specialists, endocrinologists, ultrasound doctors, and embryologists. The medical center has its own embryology laboratory and is equipped with modern equipment, some of which is a unique proprietary design.

To overcome infertility, patients can use the services of in vitro fertilization (IVF), cultivation and intrauterine implantation of the embryo. Injection of sperm into an oocyte (egg) when the parameters of the husband's sperm are poor, assisted hatching, cryopreservation (freezing) of embryos and oocytes are widely used.

During the IVF process, the service of culturing embryos for 5 days until the blastocyst stage is widely used, which increases the likelihood of pregnancy. The Embryon Medical Center is an example of a combination of affordable pricing policy and a decent level of service. Patients also highly appreciate the genuine human involvement on the part of all center staff.

There is a possibility of round-the-clock telephone communication with the attending physician.

License No. LO 77-01-007343 issued on January 9, 2014 by the Moscow Department of Health.

European Medical Center (EMC): advanced technical equipment and experienced specialists

Thanks to the work of specialists at the EMC Reproduction Clinic, more than 3,000 babies were born. EMC reproductive specialists are doctors with experience in leading European clinics.

Infertility treatment is carried out according to modern international protocols. The IVF laboratory is established in accordance with the standards of the American Society for Reproductive Medicine. If necessary, specialists at the EMC Reproduction Clinic organize consultations with the participation of reproductive specialists and doctors of other specialties.

As part of assisted reproductive technologies, EMC provides medical services such as in vitro fertilization of oocytes, intravaginal administration of drugs to stimulate egg maturation, preimplantation genetic diagnosis of the embryo and many others. Also at the European Medical Center, medical services for cryopreservation of gametes (oocytes, sperm) and embryos are available. It is possible to use donor materials (oocytes, sperm, embryos). And for women who cannot bear a child themselves, a surrogacy program can help.

License No. LO-77-01-015968 dated April 24, 2018 issued by the Moscow Department of Health

Network of clinics "Mother and Child": one of the leaders in the number of IVF cycles performed in Russia

The first Mother and Child clinic opened in Moscow in January 2006. Now the group of companies operates in 15 cities of Russia and includes 26 clinics and 4 hospitals. The network’s clinics successfully use all the capabilities of modern reproductology. Each clinic is equipped with modern technology in full compliance with international standards.

You can also highly appreciate the qualifications of the team, because all the specialists are doctors of the first and highest categories, candidates and doctors of medical sciences, professors, corresponding members of the Russian Academy of Sciences.

It is worth noting the flexible pricing policy, regular promotions, and discounts. Clients note in their reviews the comfort of the clinics and the high quality of services, as well as the responsiveness of doctors.

License No. LO-77-01-007749 was issued on February 28, 2014 by the Moscow Department of Health.

Center for Reproduction and Genetics “Nova Clinic”: high technologies and a wide range of services

A network of specialized reproduction and genetics centers provides a full range of medical services for the diagnosis and treatment of all types of infertility.

Among the competitive advantages are the following:

  • certified consumables and equipment from the world's best manufacturers;
  • many years of practical experience of doctors, many of whom are candidates and doctors of science;
  • cryopreservation of sperm, oocytes and embryos;
  • individual approach to each case;
  • application of modern technologies.

The clinics host geneticists, mammologists, endocrinologists, hemostasiologists, physiotherapists, psychologists and other specialists whose help may be required for the diagnosis and treatment of infertility.

License No. LO-77-01-015035 dated October 18, 2017, issued by the Moscow Department of Health.

“Clinic of Professor V.M. Zdanovsky”: a full range of services for infertile couples

This is one of the most famous fertility centers in the capital. The clinic includes two medical centers with impressive experience. The first IVF center was founded back in 1983 on the basis of the Second Moscow Medical Institute. And 10 years later the Lera center opened. Both centers have modern equipment, an operating room, a hospital, hormonal and clinical laboratories.

Thanks to excellent technical equipment, the clinic can quickly provide diagnostic results, carry out cryopreservation, and provide microsurgical procedures. In the “Clinic of Professor V.M. Zdanovsky” provide the following medical services: ultrasound examinations, spermograms, examination for infections, genetic examination and many others. Infertility treatment involves the provision of services within the framework of a conservative approach and assisted reproductive technologies. In addition, the clinic treats endocrinological, gynecological and urological diseases, performs hysteroresectoscopy, diagnostic laparoscopy and hysteroscopy.

License No. LO-77-01-006809 was issued on October 11, 2013 by the Moscow Department of Health.

Medical clinic “IVF Center”: from diagnosis to results

Today, the IVF Center is a network of clinics with branches in 12 cities of Russia, which offer a wide selection of infertility treatment programs.

The clinic employs not only reproductive specialists and andrologists, but also geneticists, embryologists, endocrinologists, mammologists, therapists, hematologists, immunologists, ultrasound doctors, and anesthesiologists. IVF Center has the largest bank of sperm and eggs in Russia.

Clients of the clinic note the high quality of service in their reviews. Caring for clients can also be seen in the cost of treatment: the clinic offers a variety of programs in a wide price range.

License No. LO-77-01-011143 was issued on October 27, 2015 by the Moscow Department of Health.

Medical reproduction clinic "MAMA": two-time winner of the national Crystal Test Tube award

This is one of the first private reproductive clinics in Russia; it opened in 1999. Over the years of work, the clinic’s specialists have already made more than 5,000 childless families happy. The clinic specializes in the diagnosis and treatment of infertility and early pregnancy support.

It cooperates with the largest European sperm banks, carries out preimplantation genetic diagnostics of the embryo, and provides IVF services. The clinic team - reproductive specialists, gynecologists, andrologists, embryologists, anesthesiologists - are high-level specialists with specialized education and many years of experience in medical practice in the field of ART.

The clinic's doctors are members of ESHRE, RAHR, and the Russian Association of Gynecologists and Endocrinologists. The activities of the clinic have been recognized with special professional awards. Among the advantages of the clinic are a high percentage of successful IVF, affordable prices and a lot of positive reviews from grateful clients.

License No. LO-77-01-004474 issued on December 28, 2011 by the Moscow Department of Health.

Reproductive health clinic "Bio-Optima": scientific achievements and practical experience

The center has been dealing with infertility problems since 2007. It was created on the basis of the Department of Reproductology of the Moscow Regional Research Institute of Obstetrics and Gynecology. The main task of the clinic is diagnostic and treatment services for infertility, aimed both at restoring the ability to conceive naturally and at achieving pregnancy through ART. A short list of the center's medical services: IVF, ICSI, PIXI, PGS, intrauterine sperm injection.

Most of the clinic’s specialists are scientific employees of MONIIAG. Many doctors have an academic degree of candidate or doctor of medical sciences, and are the authors of developments in reproductive medicine, practical gynecology and embryology. The clinic’s specialists regularly participate in international and Russian conferences and constantly improve their practical skills in leading clinics in Europe. Bio-Optima is aimed at an individual approach to treatment and maximum convenience for patients.

And clients, judging by the reviews, highly appreciate the attentiveness of the staff and the maximum assistance of each specialist in solving delicate problems. The clinic is also pleased with the prices for its services and regular promotions that make the services more affordable.

License No. LO-77-01-012018 was issued on April 4, 2016 by the Moscow Department of Health.

Medical Center "MirA": individual treatment and prevention regimens

This is a multidisciplinary innovation center that combines the best practices and the latest achievements in the field of reproductive and aesthetic medicine. The clinic provides a wide range of IVF services.

The MirA medical center employs world-class certified specialists, doctors of the highest category: academicians, professors, doctors and candidates of medical sciences. An integrated approach to the diagnosis and treatment of patients is implemented through the involvement of doctors of related specialties.

The clinic’s employees constantly take part in the most significant international professional congresses, forums and conferences. In accordance with the latest scientific achievements, the center is introducing promising diagnostic and treatment methods.

License No. LO-77-01-011717 was issued on January 29, 2016 by the Moscow Department of Health.

"Family Planning and Reproduction Center": conception success rate - about 40%

The IVF department was opened within the structure of the Center for Family Planning and Reproduction in 1996 and was one of the first in the country. Over the years, we have accumulated vast experience in treating infertility; more than 17,000 IVF cycles have been performed. The pregnancy rate is approximately 35–40%, which corresponds to the rates of the world's leading IVF laboratories. The latest equipment with which the department is equipped allows us to provide all high-tech ART services. The center has a laboratory for preimplantation genetic diagnostics. The clinic operates in an affordable price segment.

License No. LO-77-01-010962 was issued on September 17, 2015 by the Moscow Department of Health.

“Scientific Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakova": the founder of IVF in Russia

It was in this center that the first “test tube baby” in Russia was conceived. This happened in 1985. Since then, modern methods of infertility treatment have been continuously developed and implemented here. Thanks to the center’s specialists, more than 18,000 desired babies have already been born. The center is famous for helping in the most difficult and almost hopeless cases. Here, innovative technologies are used to identify the causes of infertility and miscarriage. The center has a bank of donor cells and embryos, provides services for cryopreservation of biomaterial, PGS at the embryo and blastocyst stage, hatching, sperm selection and fertilization using PICSI and IMSI methods.

License No. FS-99-01-009427 was issued on September 15, 2017 by the Federal Service for Surveillance in Healthcare.

Every year, more than 30 thousand protocols are implemented in Russian IVF clinics and more than 8 thousand children conceived using ART are born. IVF procedures are becoming more accessible, and interest in them is increasing year by year. The fact that the effectiveness of IVF is also increasing is encouraging. This means that the diagnosis of infertility is no longer a death sentence, but only a guide to action - look for and find your doctor and your IVF center, where they will help you find happiness!